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High Quality Sacubitril, Ahu-377 Powder CAS 149709-62-6

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AHU377 is an ethyl ester prodrug from of the neprilysin inhibitor LBQ657. Formulations containing AHU377 in combination with valsartan have been used in the treatment of mild to moderate hypertension and chronic heart failure.


Chemical Name Sacubitril
Synonyms [S-(R*,S*)]-[1,1′-Biphenyl]-4-pentanoic Acid,γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-Ethyl Ester;
CAS Number 149709-62-6
Molecular Formula C₂₄H₂₉NO₅
Appearance Off-White to Pale Yellow Sticky Solid
Melting Point No data available
Molecular Weight 411.49
Storage 4°C
Solubility Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Methanol (Sl
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications Sacubitril is an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 , is a treatment for heart failure.

Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

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