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BSTFA is a powerful trimethylsilyl donor with approximately the same donor strength as the nonfluorinated analog BSA. Advantage of BSTFA over BSA: greater volatility of its reaction products (particularly useful for GC of some lower boiling TMS amino acids).

Category: Vendor: med


Alternative Name:BSTFA

CAS Number:25561-30-2


Major Category:Metals


Category:Metalloid Compounds (Silicon)

Description:Colorless liquid; [Sigma-Aldrich MSDS]


“N,O-Bis(trimethylsilyl)trifluoroacetamide (BSTFA) is a chemical compound which is used to derivitise labile groups such as hydroxyl on other chemicals, with the more stable trimethylsilyl group, which protects the labile group and allows the compound to be used for analytical purposes or as a chemical reagent for synthesis of more complex molecules.” [Wikipedia]


Readily hydrolyzes; Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Sigma-Aldrich MSDS]


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Vendor: med

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